डॉ. मेघा कदम बेडेकर

डॉ. मेघा कदम बेडेकर
प्रधान वैज्ञानिक और प्रमुख
जलीय पर्यावरण एवं स्वास्थ्य प्रबंधन
जैव सूचना विज्ञान में एम. वी. एससी./पीएच. डी./पाठ्यक्रम
+91-22-26361446 | एक्सटेंशन: 457(O)
megha[dot]bedekar[at]cife[dot]edu[dot]in
Research Interests
- Fish vaccines
- RNA interference and CRISPR for various applications including host pathogen interaction & vaccines
- Disease diagnostics for fish
Research Papers
2025
- Rajeshwar, B.N., Kumar, T.S., Jithendran, K.P., Bedekar, M.K., Kumar, H.S., et al., 2025. Experimental infection study reveals differential susceptibilities of Penaeus monodon and Penaeus vannamei to Enterocytozoon hepatopenaei. Journal of Invertebrate Pathology, 211, p.108331.
- Akash, J.S., Vinde, P., Bedekar, M.K., Rajendran, K.V., Tripathi, G. and Krishna, G., 2025. Cloning and expression of recombinant chondroitin AC lyase protein of Flavobacterium columnare in a prokaryotic expression system. Indian Journal of Animal Research, 59(5), pp.777–784.
- Bharti, V.S., Shukla, S.P., Bedekar, M.K., Ngasotter, S. and Jha, A.K., 2025. Micro biochar derived from mango leaves and banana peduncle for efficient oxytetracycline removal from aquatic environments. Journal of Hazardous Materials Advances, 18, p.100690.
- Bedekar, M.K., Singh, A. and Teja, S.S., 2025. Mucosal fish vaccine. In: Management of Fish Diseases, pp.263–279.
- Jiji, A., Sanil, N.K., Poojary, N., Kezhedath, J., Krishnan, S., Bedekar, M.K., et al., 2025. First report of dual infection of hepatopancreatic parvovirus and Enterocytozoon hepatopenaei in wild and farmed Macrobrachium rosenbergii. Journal of Fish Diseases, e14165.
2024
- Rajeshwar, B.N., Kumar, T.S., Jithendran, K.P., Bedekar, M.K. and Rajendran, K.V., 2024. Prevalence of Enterocytozoon hepatopenaei (EHP) in Penaeus monodon farms in India. Aquaculture International, 32(7), pp.9393–9414.
- Waikhom, D., Kezhedath, J., Suresh, S.N., Bedekar, M.K., Varghese, T., et al., 2024. Induction of trained immunity using β-glucan and its protective responses in Nile tilapia, Oreochromis niloticus. Developmental & Comparative Immunology, 157, p.105188.
- Dinakaran, C., Prasad, K.P., Bedekar, M.K., Jeena, K., Acharya, A. and Poojary, N., 2024. In vitro analysis of the expression of inflammasome, antiviral, and immune genes in an Oreochromis niloticus liver cell line. Archives of Virology, 169(7), p.148.
- Chovatia, R.M., Acharya, A., Rasal, K.D., Bedekar, M.K., Jeena, K., Rathinam, R.B., et al., 2024. Ontogeny and tissue-specific expression profiles of recombination activating genes (RAGs) in Nile tilapia, Oreochromis niloticus. Gene Expression Patterns, 52, p.119358.
- Valsalam, A., Bedekar, M.K., Kezhedath, J., Sood, N., Poojary, N., Namdeo, M.S., et al., 2024. Isolation, in vitro, and in vivo pathogenicity test of Tilapia lake virus (TiLV) and lesion scoring system. Microbial Pathogenesis, 186, p.106475. Rajendran, K.V., [unclear initials], Bedekar, M.K., et al., 2024. Molecular cloning and expression of codon-optimized segment 4 protein (35 kDa) of TiLV and development of diagnostic tools. Aquaculture International, 1(1), pp.19–29. (Note: Author initials need clarification.)
2023
- Pratapa, M.G., Kumar, S., Bedekar, M.K., Kumar, H.S. and Rajendran, K.V., 2023. Experimental infection reveals Scylla serrata is less susceptible to WSSV than Scylla olivacea and Penaeus vannamei. Aquaculture, 577, p.739877.
- Pratapa, M.G., Kumar, S., Bedekar, M.K., Kumar, H.S. and Rajendran, K.V., 2023. Pathogenicity of WSSV after multiple passages in Scylla olivacea. Journal of Invertebrate Pathology, 201, p.108016.
- Valsalam, A., Rajendran, K.V., Kezhedath, J., Godavarikar, A., Sood, N., Bedekar, M.K., et al., 2023. Development of an indirect ELISA for detecting TiLV in fish tissues and mucus. Journal of Virological Methods, 315, p.114707.
- Valsalam, A., Gireesh-Babu, P., Rajendran, K.V., Tripathi, G. and Bedekar, M.K., 2023. Re-engineering of bicistronic plasmid to co-express GAPDH and IFN from Edwardsiella tarda. Indian Journal of Experimental Biology, 61(3), pp.204–213.
- Valsalam, A. and Bedekar, M.K., 2023. An understanding of the bacterial evasion strategies from host immune response. Journal of Indian Fisheries Association, 48(2).
- Valsalam, A., Rajendran, K.V., Vinde, P. and Bedekar, M.K., 2023. Optimisation of transformation of fusion gene GAPDH-IFN in E. coli. Indian Journal of Fisheries, 70(2).
2022
- Subramaniyan, A.J., Prasad, K.P., Kumar, S., Poojary, N., Valsalam, A., Bedekar, M.K., et al., 2022. Comparative analysis of Hsp70 and Hsp90 gene expression in Labeo rohita challenged with live and killed E. tarda. Acta Scientific Microbiology, 5(11).
- Bedekar, M.K., Kole, S. and M., M., 2022. Types of vaccines used in aquaculture. In: Fish Immune System and Vaccines, pp.45–63.
- Makesh, M., Vinay, T.N. and Bedekar, M.K., 2022. Methods of vaccine delivery. In: Fish Immune System and Vaccines, pp.217–230.
- Makesh, M. and Rajendran, K.V., 2022. Fish Immune System and Vaccines. Springer.
- Bedekar, M.K. and Kole, S., 2022. DNA vaccines for fish. In: Advances in Fisheries Biotechnology, pp.289–336.
- Bedekar, M.K. and Kole, S., 2022. Vaccine design: Methods and protocols. In: Vaccines for Veterinary Diseases, Springer US.
- Bedekar, M.K. and Rajendran, R.K.V., 2022. Overview of fish immune system. In: Fish Immune System and Vaccines, pp.1–16.
2021
- Bedekar, M.K. and Kole, S., 2021. Development of nano-conjugated DNA vaccine against Edwardsiella in fish. In: Vaccine Design: Methods and Protocols, Springer.
- Bedekar, M.K. and Kole, S., 2021. Fundamentals of fish vaccination. In: Vaccine Design: Methods and Protocols, Springer.
- Valappil, R.K., Anand, D., Kulkarni, A., Mahapatra, M., Kumar, S.H., Bedekar, M.K., et al., 2021. Three draft genome sequences of WSSV from India. Microbiology Resource Announcements, 10(34), e00579-21.
- Chowdhury, D.K., Sahu, N.P., Sardar, P., Deo, A.D., Bedekar, M.K., Singha, K.P., et al., 2021. Physio-immunological responses of Labeo rohita to phytogenic feed additives. Journal of Environmental Biology, 41(6), pp.1455–1463.
List of Technologies Developed & Commercialized
- Immersion-based whole-cell Killed vaccine against Edwardsiella tarda
- Immersion-based whole-cell Killed vaccine against Flavobacterium columnare
- Immersion-based whole-cell Killed vaccine against Aeromonas veronii
- Immersion-based whole-cell killed vaccine for E. tarda and F. columnare (Field trial and commercialization)
1. National Surveillance Programme for Aquatic Animal Diseases (NSPAAD), Referral Laboratory
- Role: Principal Investigator (PI)
- Funding Agency: Department of Fisheries, Ministry of Fisheries, Animal Husbandry and Dairying, Government of India
- Project Type: National Referral Laboratory under NSPAAD
- Objective: Surveillance, early detection, and reporting of listed aquatic animal diseases in India through a nationwide diagnostic and reporting framework.
- Duration: Ongoing
2. All India Network Project on Fish Health
- Role: Principal Investigator (PI)
- Funding Agency: Indian Council of Agricultural Research (ICAR)
- Objective: To monitor fish health status across major aquaculture species and regions in India, develop mitigation strategies for emerging diseases, and establish diagnostic and management protocols.
- Duration: Ongoing
3. Development of CRISPR-based Rapid Diagnostics for Emerging Aquatic Pathogens
- Role: Principal Investigator (PI)
- Funding Agency: Indian Council of Agricultural Research (ICAR)
- Objective: To develop rapid, field-deployable CRISPR-LFA diagnostics for priority aquatic pathogens such as White Spot Syndrome Virus (WSSV) and Tilapia Lake Virus (TiLV).
- Duration: Ongoing
- Status: TiLV and WSSV CRISPR assays developed; patents filed; commercialization in progress.
Significant achievements in research & development
- Development of vaccine for bacterial pathogens of fish.
- Development of diagnostics for fish and poultry pathogens
Honours / Awards
- Institutional Best Scientist Award at Institute for year 2024-25
- Best institutional building scientist award 2018-19
- पिछले पृष्ठ पर वापस जाएँ
- |
-
पृष्ठ अंतिम अद्यतन तिथि:14-08-2025 05:19 PM